Why do Moldovans make some of the best wires?
Journo Birds July 17, 2024
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Ultra-thin Moldovan metal wires help us understand the brain better.
One simple question connects some of the best neuroscientists in the world and an abandoned Soviet factory: How can we understand the brain better?
We know very little about something so vital to us. Researchers have gotten most data from images or EEG (metal disks placed on the head). But these methods don't give us a complete picture of what is happening within our brain cells.
“Imagine you wanted to assess what the voters think by standing in the middle of London. You would only hear the murmur, or maybe an occasional scream from an angry voter,” Mihaly Kollo, a London-based neuroscientist, explained. “But to understand what they are really saying, you would have to speak to each voter individually.”
So the question is: how can you reach those individual “Voters” or tiny brain cells? You would need something very, very thin.
In Germany, in the early 2010s, a group of researchers—including Kollo— were trying to understand the brain. They wanted to record the electrical activity of each cell.
Kollo's supervisor, Andreas Schaefer, had an idea. He proposed connecting CMOS chips (similar to the ones in cameras) to insulated metal wires, inserting them inside the brain, and recording brain activity.
“I thought that was a very good idea!” Kollo told me. His lab partner, Matt Angle, went along with the idea and decided to develop it further.
But for it to work, you need very thin and efficient wires. Angle found out about a factory called Eiliri in Moldova. Founded in 1959, it served as a research institute for electrical instruments.
Eliri's researchers used a unique technique, the Taylor Ulitovski process, to create well-insulated wires. They placed metal inside a glass tube and heated it until it melted. They then pulled it into a very thin thread. Even MIT Technology Review wrote, "The key to solving one of neuroscience’s most intractable challenges lay in a 1960s-era technology invented in the tiny nation of Moldova.”
It was a “very elegant way” to make wires of diameters that could never have been drawn conventionally. “They were unique!” Angle shared. To his knowledge, Moldova makes some of the thinnest and longest nanowires in the world.
That discovery inspired him to visit Moldova as a young researcher.
Invisible military technology
This building, in Moldova's capital, Chisinau, is a dozen stories tall and full of old computers and technology from the 1970s. There are wires everywhere. On one wall, Lenin peaks out behind old panels. It was once hiding some of the Soviet's top secrets. You couldn't just walk in. Now, it stands empty, and anything futuristic that may have been here once has been degraded into an echoing museum.
“The director came to me very proudly and showed me a piece of rubber,” Angle recalls his visit. “It looked like a simple rubber tire. Very flexible. He said it was impregnated with microwires. Then he winked at me and said: “Completely invisible to an American radar.” In other words, Stealth technology.”
Angle felt like he was in a James Bond movie. The building was full of interesting stories. “It was an incredible visit!” the US researcher recalls. He brought Eliri's wires back to Stanford University, where he was then doing postdoctoral research.
Not long later, another future entrepreneur stepped into the old factory.
Factory rising from the dust
Marcel Varlan, a Moldovan consultant with an engineering and business background, was sent to review Eliri. He had to assess what should be done with this crumbling real estate and the around six retiring researchers the company still employed.
We meet Varlan in his Chisinau-based training center and lab. He tells us he saw an opportunity. “Everything is getting smaller and more complex,” he told us. “Not long ago, computers were the size of a room. Now they are the size of a palm.”
Varlan decided to take over the company's leading position1.
He started researching, searching the internet, talking to people, and going to conferences. He quickly understood bringing an old Soviet factory back to life was much harder than anticipated. Nanowires are a very specific, niche technology. “A long time ago, Eliri had around 500 engineers developing wires and applications,” Varlan explained. “Nowadays, it's all gone. You need the whole system and flow, from wire manufacturing technology to integration, testing, and mass deployment. We had to almost start from scratch!”
Half a year later, a Spanish company turned to Eliri with “a huge request” for micro-wires. For Varlan, it meant increasing the production capacity by 50 times almost overnight. “There was no equipment or available people!” he remembers the panic. He started looking around where to buy the equipment.
But nothing like this was on sale. Varlan complained to his uncle, who responded: “Build it yourself! You're an engineer!”
Varlan: “That was the exact moment I was reborn as an engineer, and I started building.” In parallel, he was building the team. “It was crazy! And we succeeded. We built the first and the second equipment.”
The project with the Spanish company fell through, but it was a good enough trigger to kickstart the new phase of Eliri, a company rising from the dust.
“We started feeling confident about our capacity and ways of fast-designing equipment and building technologies,” Varlan said. He shows us some of the old Soviet equipment he brought from the old factory. He keeps them here as artifacts, as a reminder of the past.
Even though Varlan speaks a lot about chances and hunches, his office and lab don't give any hints of impulsiveness. His perfectly clean table only has one charging cable on it.
Most of the equipment in his new lab is built by himself and his staff, whom he educates in-house. He doesn't expect his young employees to know everything but to be willing to learn and try. He believes that students who have finished university lack creativity and are not able to apply outdated theories.
Even though the production moved to the new building, the secrecy is still there. Varlan shows us around with one condition: no photos or videos can be taken here. It's a top secret - once again!
Chips in our Brains
Angle ended up not using Eliri's wires in his current lab. He is now the head of Paradromics, a leading developer of brain-computer interfaces and one of Elon Musk's Neuralink's biggest competitors.
Mihaly Kollo is now at the Francis Crick Institute, a leading biomedical research center in London, and still orders Eliri's golden nanowires.
He wants to understand the brain so that he can heal it.
Kollo predicts that soon, instead of pills, some mental diseases like Parkinson's disease will be treated by using stimulating chips that are inserted into brains.
“I think we are close,” he said excitedly.
Correction / Clarification: In the original version of this article it stated that “Varlan decided to take over the company's leading position and turn it into a million-dollar nanowire production company.” We’ve chosen to remove the part about the million dollar company to clarity. Records do not show Eliri as a million dollar company but it may reflect the company’s aspirations. For simplicity we’ve removed this sentence.
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I suspect I’m not the only one who looked at the headline ant thought it should have been Wine!
A great article with information completely new to me.